Organic Chicken Bone Broth

Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312‐321. Published 2009 Oct 9. doi: 10.7150/ijms.6.312

Bakilan F, Armagan O, Ozgen M, Tascioglu F, Bolluk O, Alatas O. Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial. Eurasian J Med. 2016;48(2):95‐101. doi: 10.5152/eurasianjmed.2015.15030

Lugo, J.P., Saiyed, Z.M. & Lane, N.E. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J 15, 14 (2015). DOI: 10.1186/s12937-016-0130-8

Bagchi, D., Misner, B., Bagchi, M., Kothari, S. C., Downs, B. W., Fafard, R. D., & Preuss, H. G. (2002). Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. International journal of clinical pharmacology research, 22(3-4), 101–110.

Zhu, P., Li, X. Y., Wang, H. K., Jia, J. F., Zheng, Z. H., Ding, J., & Fan, C. M. (2007). Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis. Clinical immunology (Orlando, Fla.), 122(1), 75–84. DOI: 10.1016/j.clim.2006.08.004

Barnett, M. L., Kremer, J. M., St Clair, E. W., Clegg, D. O., Furst, D., Weisman, M., Fletcher, M. J., Chasan-Taber, S., Finger, E., Morales, A., Le, C. H., & Trentham, D. E. (1998). Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis and rheumatism, 41(2), 290–297. DOI: 10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R

Yoshinari, O., Moriyama, H., & Shiojima, Y. (2015). An overview of a novel, water-soluble undenatured type II collagen (NEXT-II). Journal of the American College of Nutrition, 34(3), 255–262. DOI: 10.1080/07315724.2014.919541

Paul, C., Leser, S., & Oesser, S. (2019). Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients, 11(5), 1079. DOI: 10.3390/nu11051079

Darling, A. L., Manders, R., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., & Lanham-New, S. A. (2019). Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 30(4), 741–761. DOI: 10.1007/s00198-019-04933-8

Lerman, R. H., Chang, J. L., Konda, V., Desai, A., & Montalto, M. B. (2015). Nutritional Approach for Relief of Joint Discomfort: A 12-week, Open-case Series and Illustrative Case Report. Integrative medicine (Encinitas, Calif.), 14(5), 52–61. PMCID: PMC4712866

Organic Bovine Bone Broth

Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7. doi: 10.3390/ijms19103059

Saha A, Alam MJ, Ashraf KU, Mannan A. Computational analysis of bovine alpha-1 collagen sequences. Bioinformation. 2013;9(1):42‐48. doi: 10.6026/97320630009042

León-López A, Morales-Peñaloza A, Martínez-Juárez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Álvarez G. Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031. Published 2019 Nov 7. doi: 10.3390/molecules24224031

K. Henriksen, M.A. Karsdal, in Biochemistry of Collagens, Laminins and Elastin, 2016

Albaugh VL, Mukherjee K, Barbul A. Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. J Nutr. 2017;147(11):2011‐2017. doi:10.3945/jn.117.256404

Avila Rodríguez, MI, Rodríguez Barroso, LG, Sánchez, ML. Collagen: A review on its sources and potential cosmetic applications. J Cosmet. Dermatol. 2018; 17: 20– 26. DOI: 10.1111/jocd.12450

Paul C, Leser S, Oesser S. Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients. 2019;11(5):1079. Published 2019 May 15.  doi: 10.3945/jn.117.256404

Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47–55. DOI: 10.1159/000351376

Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, König D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237‐1245. doi: 10.1017/S0007114515002810

Organic Ashwagandha

Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255–262. doi: 10.4103/0253-7176.106022

BHATIA, V. and TANDON, R.K. (2005), Stress and the gastrointestinal tract. Journal of Gastroenterology and Hepatology, 20: 332-339. doi:10.1111/j.1440-1746.2004.03508.x

Singh SK, Rajoria K. Ayurvedic management of chronic constipation in Hirschsprung disease - A case study. J Ayurveda Integr Med. 2018;9(2):131–135. doi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033722/

Mishra, L.C. & Singh, B.B. & Dagenais, Simon. (2000). Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): A Review. Alternative medicine review : a journal of clinical therapeutic. 5. 334-46. https://www.researchgate.net/publication/12365397_Scientific_basis_for_the_therapeutic_use_of_Withania_somnifera_Ashwagandha_A_Review

Organic Turmeric Extract

Hewlings SJ, Kalman DS. Curcumin: A Review of Its' Effects on Human Health. Foods. 2017;6(10):92. Published 2017 Oct 22. doi.org/10.3390/foods6100092.

Langhans, Sigrid. (2011). Therapeutic potential of curcumin in gastrointestinal diseases. World journal of gastrointestinal pathophysiology. 2. 1-14. DOI: 10.4291/wjgp.v2.i1.1

Adrian L Lopresti, The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?, Advances in Nutrition, Volume 9, Issue 1, January 2018, Pages 41–50, https://doi.org/10.1093/advances/nmx011

Chainani-Wu N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Journal of alternative and complementary medicine (New York, N.Y.), 9(1), 161–168. DOI: 10.1089/107555303321223035

Zdrojewicz, Z., Szyca, M., Popowicz, E., Michalik, T., & Śmieszniak, B. (2017). Kurkuma – nie tylko przyprawa [Turmeric - not only spice]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 42(252), 227–230. PMID: 28662006

Gupta, S. C., Sung, B., Kim, J. H., Prasad, S., Li, S., & Aggarwal, B. B. (2013). Multitargeting by turmeric, the golden spice: From kitchen to clinic. Molecular nutrition & food research, 57(9), 1510–1528. DOI: 10.1002/mnfr.201100741

Organic Alma Berry Extract

Baliga, M. S., & Dsouza, J. J. (2011). Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 20(3), 225–239. DOI: 10.1097/CEJ.0b013e32834473f4

Scartezzini, P., Antognoni, F., Raggi, M. A., Poli, F., & Sabbioni, C. (2006). Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn. Journal of ethnopharmacology, 104(1-2), 113–118. DOI: 10.1016/j.jep.2005.08.065

Fujii, T., Wakaizumi, M., Ikami, T., & Saito, M. (2008). Amla (Emblica officinalis Gaertn.) extract promotes procollagen production and inhibits matrix metalloproteinase-1 in human skin fibroblasts. Journal of ethnopharmacology, 119(1), 53–57. DOI: 10.1016/j.jep.2008.05.039

Chen, T. S., Liou, S. Y., & Chang, Y. L. (2009). Supplementation of Emblica officinalis (Amla) extract reduces oxidative stress in uremic patients. The American journal of Chinese medicine, 37(1), 19–25. DOI: 10.1142/S0192415X09006680

Poltanov, E. A., Shikov, A. N., Dorman, H. J., Pozharitskaya, O. N., Makarov, V. G., Tikhonov, V. P., & Hiltunen, R. (2009). Chemical and antioxidant evaluation of Indian gooseberry (Emblica officinalis Gaertn., syn. Phyllanthus emblica L.) supplements. Phytotherapy research : PTR, 23(9), 1309–1315. DOI: 10.1002/ptr.2775

Chen, T. S., Liou, S. Y., Wu, H. C., Tsai, F. J., Tsai, C. H., Huang, C. Y., & Chang, Y. L. (2011). Efficacy of epigallocatechin-3-gallate and Amla (Emblica officinalis) extract for the treatment of diabetic-uremic patients. Journal of medicinal food, 14(7-8), 718–723. DOI: 10.1089/jmf.2010.1195

Zhao T, Sun Q, Marques M, Witcher M. Anticancer Properties of Phyllanthus emblica (Indian Gooseberry). Oxid Med Cell Longev. 2015;2015:950890. doi: 10.1155/2015/950890